Description: Consumer groups fear that the use of genetic testing information in insurance underwriting might lead to the creation of an underclass of individuals who cannot obtain insurance. Thus, these groups want to ban insurance companies from accessing genetic test results. Insurers contend that such a ban might lead to adverse selection that could threaten their financial solvency. To investigate the potential effect of adverse selection in a term life insurance market, a discrete-time, discrete-state, Markov chain is used to track the evolution of 12 closed cohorts of women, differentiated by family history of breast and ovarian cancer and age-at-issue of a 20-year annually renewable term life insurance policy. The insurance demand behavior of these women is tracked, incorporating elastic demand for insurance. During the 20-year period, women may get tested for BRCA 1/2 mutations. Each year, the insurer calculates profits/losses to date and expected future benefit payouts which determines the following year’s premium schedule. At the end of each policy year, women can change their life insurance benefit, influenced by their testing status and premium changes. Adverse selection could result from differentiated: 1. benefits following test results, 2. lapse rates according to test results, and 3. reactions to price increases. It is concluded that with realistic estimates of behavioral parameters, adverse selection should be a manageable problem for insurers. From Actuarial Research Clearing House 2004, Vol. 1.