The advent of emerging technologies such as blockchain, decentralized AI, and advanced privacy preserving techniques have created the possibility that billions of individuals may be able to maintain sovereignty and control of their own data. As data becomes increasingly valuable as the means of production for a variety of digital goods and services, this self-sovereignty of data may create a new economic framework of individualized data monetization. This session will explore the key factors, technologies and mega-trends in health and medicine aligning to drive this new economy and explore what the future may look like from a data valuation perspective as the current $120 billion secondary market for health data expands to include consented health and health-relevant data from more individuals, to the benefit of all individuals and the healthcare system as a whole.